We are an international and interdisciplinary laboratory aiming to bridging the gap between structural and cell biology, particularly to decipher the mechanical aspects of how cells sense and react to their environment.
This includes asking how cells employ forces to probe the interaction to other molecules such as receptor-ligand interactions to switch biochemical function, i.e. T-cell activation, migration or their interaction with the extracellular matrix. Furthermore, we investigate how these insights can be exploited for biomedical applications.
We use state-of-the-art single molecule microscopy techniques such as super-resolution microscopy, AFM and optical tweezer to gain insights into general aspects of mechanobiology, membrane biophysics, neurobiology and immunology.
Hasan Simsek receives support from Carl Friedrich von Siemens Stiftung and Alexander von Humboldt Stiftung for his third year in the Mechanobiology lab of Professor Klotzsch
Dominic joins the team in Berlin to work on the recently DFG funded project on B-cell activation
Tamara presented her work within the Mechanobiology Seminar at ETH Zurich.
Our lab has just received funding from DFG to work on the mechanobiological aspects
Together with Dr. Dimi Wagner from Charite, we wrote a research highlight on T cells in a tumor
Together with my former collegues and friends from Vienna, Kopenhagen and Leeds
Congratulations Hasan on his review about T cells in a tumor microenvironment that has been
Congrats Dani and Willi on their new work on an open hardware design for a spin coater
Big welcome to our new master students Tido Willms and Yusuf Alkan, who will join both our Berlin
"Well done running crew!" Big hands up for Anja, Marcia and Enrico for running for the Vogelschar team